SYSTEMS NEUROSCIENCE N623 - Week 16
Learning and Memory: Cellular Mechanisms

Nobel of the Week

  • 2000 - Arvid Carlsson, Paul Greengard and Eric R. Kandel "for their discoveries concerning signal transduction in the nervous system", focus on Greengard and Kandel.

    Introductory Readings for discussion on December 5.

  • Principles of Neuroscience (2000) eds. Kandel, ER, Schwartz, JH, and Jessell, TM. Chapter 62.
  • Parker, ES, Cahill, L, McGaugh, JL (2006) A case of unusual autobiographical remembering. Neurocase 12: 35-49.

    Additional readings for discussion on December 5.

  • Scoville WB and Milner B (1957) Loss of recent memory after bilateral hippocampal lesions. J. Neurol. Neurosurg. Psychiat. 20:11-21.
  • Morris RGM, Garrud P, Rawlins JNP, and O'Keefe J. (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297:681-683.

    Introductory Readings for discussion on December 8.

  • Principles of Neuroscience (2000) eds. Kandel, ER, Schwartz, JH, and Jessell, TM. Chapter 63.

    Original Literature Readings for discussion on December 8.

  • Kandel ER and Schwartz JH (1982) Molecular biology of learning: Modulation of transmitter release. Science 218:433-443.
  • Chain DG, Casadio A, Schacher S, Hegde AN, Valbrun M, Yamamoto N, Goldberg AL, Bartsch D, Kandel ER and Schwartz JH (1999) Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia. Neuron 22:147-156.

    Original Literature Readings for discussion on May 12.

  • Drier EA, Tello MK, Cowan M, Wu P, Blace N, Sacktor TC, and Yin JCP (2002) Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster. Nature Neurosci. 5:316-324.
  • Lamprecht R, Hazvi S, and Dudai Y (1997) cAMP response element-binding protein in the amygdala is required for long- but not short-term conditioned taste aversion memory. J. Neurosci. 17:8443-8450.
  • Bliss TVP, Collingridge (1993) A synaptic model of memory: long term potentiation in the hippocampus. Nature 361:31-39.

     

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