Smell and Taste: The Chemical Senses

Nobel of the Week

  • 2004 - Richard Axel and Linda B. Buck, "for their discoveries of odorant receptors and the organization of the olfactory system"

    Introductory Readings for discussion on October 22.

  • Kandel, Schwartz, Jessell, Chapter 32.

    Original Literature Readings for discussion on October 24.

  • Malnic, B, Hirono, J, Sato, T, and Buck, LB. (1999) Combinatorial receptor codes for odors. Cell 96:713-723.
  • Iwema, CL, Fang, H, Kurtz, DB, Youngentob, SL, and Schwob, JE. (2004) Odorant receptor expression patterns are restored in lesion-recovered rat olfactory epithelium. J. Neurosci. 24:356-369.
  • Kent, PF, Mozell, MM, Youngentob, SL, and Yurco, P. (2003) Mucosal activity patterns as a basis for olfactory discrimination: Comparing behavior and optical recordings. Brain Res. 981:1-11.

    Original Literature Readings for discussion on October 27.

  • Mombaerts, P, Wang, F, Dulac, Chao, SK, Nemes, A, Mendelsohn, Edmonson, J, and Axel R. (1996) Visualizing an olfactory sensory map. Cell 87:675-686.
  • Meister, M, and Bonhoeffer, T. (2001) Tuning and topography in an odor map on the rat olfactory bulb. J. Neurosci. 21:1351-1360.
  • Johnson, BA, Ho, SL, Xu, Z, Yihan, JS, Yip, S, Hingco, EE, and Leon, M. (2002) Functional mapping if the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features. J. Comp. Neurol. 449:180-194.
  • Zou, Z, Horowitz, L, Montmayeur, JP, Snapper, Buck, L. (2001) Genetic tracing reveals a stereotyped sensory map in the olfactory cortex. Nature 414:173-179.