SYSTEMS NEUROSCIENCE N623 - Week 9
Smell and Taste: The Chemical Senses
Nobel of the Week
2004 - Richard Axel and Linda B. Buck, "for their discoveries of odorant receptors and the organization of the olfactory system"
Introductory Readings for discussion on October 26.
Kandel, Schwartz, Jessell, Chapter 32, or Purves et al (2018) Chapter 15.
Original Literature Readings for discussion on October 30.
Malnic, B, Hirono, J, Sato, T, and Buck, LB. (1999) Combinatorial receptor codes for odors. Cell 96:713-723. Kent, PF, Mozell, MM, Youngentob, SL, and Yurco, P. (2003) Mucosal activity patterns as a basis for olfactory discrimination: Comparing behavior and optical recordings. Brain Res. 981:1-11.
Original Literature Readings for discussion on October 31.
Johnson, BA, Ho, SL, Xu, Z, Yihan, JS, Yip, S, Hingco, EE, and Leon, M. (2002) Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features. J. Comp. Neurol. 449:180-194. Zou, Z, Horowitz, L, Montmayeur, JP, Snapper, Buck, L. (2001) Genetic tracing reveals a stereotyped sensory map in the olfactory cortex. Nature 414:173-179.