Sensory Experience, Plasticity and Reorganization

Introductory Readings for discussion on Dec 15.

  • Principles of Neuroscience (2013) Fifth Edition, eds. Kandel, ER, Schwartz, JH, Jessell, TM and Hudspeth, J. Chapters 17 (pp 373-383), 56.
  • Wiesel, TN (1981) The postnatal development of the visual cortex and the influence of environment. Nobel Lecture 12/8/1981.

    Quickie Demos

  • Perceptual fill-in of your blindspot.
  • Neon spreading.
  • More neon spreading.
  • Powerpoint of more blindspot and fill-in demos.

    Original Literature Readings for discussion on Dec 15.

  • Ramachandran (2000) Phantom limbs and neural plasticity. Arch. Neurol. 57: 317-320.
  • Gilbert, CD and Wiesel, TN (1992) Receptive field dynamics in adult primary visual cortex, Nature 356:150-152.
  • Homare Yamahachi, Sally A. Marik, Justin N.J. McManus, Winfried Denk and Charles D. Gilbert. (2009) Rapid Axonal Sprouting and Pruning Accompany Functional Reorganization in Primary Visual Cortex. Neuron 64(5):719-729.
  • Smirnakis, S. M., A. A. Brewer, M. C. Schmid, A. S. Tolias, A. Schüz, M. Augath, W. Inhoffen, B. A. Wandell and N. K. Logothetis (2005) Lack of long-term cortical reorganization after macaque retinal lesions. Nature 435, 300-307. (You may skim this article.) [A rebuttal/exchange about this controversy.]

    Optional Readings

  • Buonomano, DV and Merzenich, MM (1998) Cortical Plasticity: From Synapses to Maps. Annu. Rev. Neurosci. 21: 149-186.
  • Darian-Smith, C and Gilbert, CD (1994) Axonal sprouting accompanies functional reorganization in adult cat striate cortex, Nature 368:737-740.
  • Darian-Smith and Gilbert (1995) Topographic reorganization in the striate cortex of the adult cat and monkey is cortically mediated. J. Neurosci. 15:1631-1647.
  • Kaas, Krubitzer, Chino, Langston, Polley and Blair (1990) Reorganization of retinotopic cortical maps in adult mammals after lesions of the retina, Science 248:229-231.
  • Baker, CI, Peli, E, Knouf, N, Kanwisher, NG. (2005) Reorganization of Visual Processing in Macular Degeneration J. Neurosci. 25: 614-618.
  • Florence, SL, Taub, HB, Kaas, JH (1998) Large-scale sprouting of cortical connections after peripheral injury in adult macaque monkeys. Science 282: 1117-1121.
  • Jones, EG, Pons, TP (1998) Thalamic and brainstem contributions to large-scale plasticity of primate somatosensory cortex. Science 282: 1117-1121.
  • Recanzone (2000) Cerebral cortical plasticity: Perception and skill acquisition, In: The New Cognitive Neuroscience, MS Gazzaniga, ed. 237-247.
  • Ramachandran (1993) Behavioral and magnetoencephalographic correlates of plasticity in the adult human brain. PNAS 90:10413-10430.
  • Moore, CI, Stern, CE, Dunbar, C, Kostyk, SK, Gehi, A, Corkin , S. (2000) Referred phantom sensations and cortical reorganization after spinal cord injury in humans. PNAS 97: 14703-14708.

    Original Literature Readings for discussion on Dec 18.

  • Knudsen EI. (2002) Instructed learning in the auditory localization pathway of the barn owl. Nature 417: 322-328.
  • Polley, DB, Steinberg, EE, Merzenich, MM. (2006) Perceptual learning directs auditory cortical map reorganization through top-down influences. J. Neurosci. 26: 4970-4982.
  • Rauschecker, JP (1995) Compensatory plasticity and sensory substitution in the cerebral cortex. TINS 18: 36-43.
  • Cohen, LG, Celnik, P, Pascual-Leone, A, Corwell, B, Faiz, L, Dambrosia, J, Honda, M, Sadato, N, Gerloff, C, Catala´, MD, Hallett, M. (1997) Functional relevance of cross-modal plasticity in blind humans. Nature 389:180-183.

    Optional Readings

  • Gould, E, Reeves, AJ, Graziano, MSA, Gross, CG (1999) Neurogenesis in the neocortex of adult primates. Science 286: 548-552.
  • Doupe, AJ and Kuhl, PK (1999) Birdsong and human speech: Common themes and mechanisms. Annu. Rev. Neurosci. 22: 567-631.
  • Knudsen and Brainard (1991) Visual instruction of the neural map of auditory space in the developing optic tectum, Science 253:85-87.
  • Brainard and Knudsen (1993) Experience-dependent plasticity in the inferior colliculus: A site for visual calibration of the neural representation of auditory space in the barn owl, J. Neurosci. 13:4589-4608.
  • Hyde PS, Knudsen EI (2002) The optic tectum controls visually guided adaptive plasticity in the owl's auditory space map. Nature 415: 73-76.
  • Recanzone, GH (1998) Rapidly induced auditory plasticity: The ventriloquism aftereffect. PNAS 95(3): 869 - 875.
  • Schwab, ME (2002) Repairing the injured spinal cord. Science 295: 1029-1031.
  • Woolf, CJ, Salter, MW (2000) Neuronal Plasticity: Increasing the gain in pain. Science 288:1765-1768.
  • Rakic, P, Suner, I, and Williams, RW (1991) A Novel Cytoarchitectonic Area Induced Experimentally Within the Primate Visual Cortex. PNAS 88: 2083-2087.
  • Kahn, DM and Krubitzer, L. (2002) Massive cross-modal cortical plasticity and the emergence of a new cortical area in developmentally blind mammals. PNAS 99(17): 11429 - 11434.
  • Rakic, P (1985) Limits of neurogenesis in primates. Science 227: 1054-1056.
  • Gould, E, Reeves, AJ, Graziano, MSA, Gross, CG (1999) Neurogenesis in the neocortex of adult primates. Science 286: 548-552.
  • Von Melchner, L., Pallas, S.L. and Sur, M. (2000) Visual behavior mediated by retinal projections directed to the auditory pathway. Nature 404:871-876.