Central Audition, from Cochlear Nucleus to Auditory Cortex

Nobel of the Week

  • 2000 - Arvid Carlsson, Paul Greengard and Eric R. Kandel, "for their discoveries concerning signal transduction in the nervous system" (focus on Kandel).

    Introductory and Original Literature Readings for discussion on October 17.

  • Review Kandel, Schwartz, Jessell, Chapter 30, pp. 603-613.
  • Chapter 6, The Brainstem Nuclei, from Pickles J.O., An Introduction to the Physiology of Hearing, 2nd edition, London:Academic Press, 1988.
  • Chapter 7, The Auditory Cortex, ibid.
  • Imig, TJ, Brugge, JF. (1978) Sources and terminations of callosal axons related to binaural and frequency maps in primary auditory cortex of the cat. J. Comp. Neur. 182: 637-660.
  • Tian, B, Reser, D, Durham, A, Kustov, A, Rauschecker, JP. (2001) Functional specialization in rhesus monkey auditory cortex. Science 292: 290-293.

    Original Literature Readings for discussion on October 20.

  • Cheung, SW, Bedenbaugh, PH, Nagarajan, SS, and Schreiner, CE, (2001) Functional Organization of Squirrel Monkey Primary Auditory Cortex: Responses to Pure Tones. J Neurophysiol 85: 1732 - 1749.
  • Knudsen, EI, Konishi, M. (1978) Space and frequency are represented separately in auditory midbrain of the owl. J. Neurophys. 41: 870-884.
  • Picture of an Owl's head.
  • Video clip of an owl catching a mouse in total darkness.
  • Suga, N, Jen, PHS. (1976) Disproportionate tonotopic representation for processing CF-FM sonar signals in the mustache bat auditory cortex. Science 194: 542-544.
  • Video clip of a bat catching a moth using sonar.
  • Suga, N, O'Neill, WE, Manabe, T. (1978) Cortical neurons sensitive to combinations of information-bearing elements of biosonar signals in the mustache bat. Science 200: 778-781
  • Suga, N. O'Neill, WE. (1979) Neural axis representating target range in the auditory cortex of the mustache bat. Science 206: 351-353.

    Optional Readings

  • Wang, X, Merzenich, M, Beitel, R and Schreiner, CE. (1995) Representations of a species-specific vocalization in the primate auditory cortex of the common marmoset: Temporal and spatial characteristics. J. Neurophys. 74: 2685-2706.