Basal Ganglia

Nobel of the Week

  • 2000 - Arvid Carlsson, Paul Greengard and Eric R. Kandel "for their discoveries concerning signal transduction in the nervous system", focus on Carlsson.

    Introductory Readings for discussion on November 29.

  • Principles of Neuroscience (2013) Fifth Edition, eds. Kandel, ER, Schwartz, JH, and Jessell, TM. Chapter 43.

    Additional background reading - highly relevant to information presented in class:

  • Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381.

    Original Literature Readings for discussion on November 29.

  • Crutcher MD, DeLong MR (1984) Single cell studies of the primate putamen. I. Functional organization. Exp Brain Res 53:233-43.
  • Hikosaka O, Wurtz RH (1983) Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses. J Neurophysiol. 49:1268-84.
  • Schultz W (1986) Activity of pars reticulata neurons of monkey substantia nigra in relation to motor, sensory, and complex events. J Neurophysiol 55:660-77.
  • Kawagoe R, Takikawa Y, Hikosaka O (1998) Expectation of reward modulates cognitive signals in the basal ganglia. Nat Neurosci 1:411-6.