SYSTEMS NEUROSCIENCE N623 - Week 13
Nobel of the Week
2000 - Arvid Carlsson, Paul Greengard and Eric R. Kandel "for their discoveries concerning signal transduction in the nervous system", focus on Carlsson.
Introductory Readings for discussion on November 29.
Principles of Neuroscience (2013) Fifth Edition, eds. Kandel, ER, Schwartz, JH, and Jessell, TM. Chapter 43.
Additional background reading - highly relevant to information presented in class:
Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381.
Original Literature Readings for discussion on November 29.
Crutcher MD, DeLong MR (1984) Single cell studies of the primate putamen. I. Functional organization. Exp Brain Res 53:233-43. Hikosaka O, Wurtz RH (1983) Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses. J Neurophysiol. 49:1268-84. Schultz W (1986) Activity of pars reticulata neurons of monkey substantia nigra in relation to motor, sensory, and complex events. J Neurophysiol 55:660-77. Kawagoe R, Takikawa Y, Hikosaka O (1998) Expectation of reward modulates cognitive signals in the basal ganglia. Nat Neurosci 1:411-6.